diff --git a/python/sglang/srt/hardware_backend/npu/quantization/moe_methods.py b/python/sglang/srt/hardware_backend/npu/quantization/moe_methods.py
index 833b81755..8c5534984 100644
--- a/python/sglang/srt/hardware_backend/npu/quantization/moe_methods.py
+++ b/python/sglang/srt/hardware_backend/npu/quantization/moe_methods.py
@@ -282,6 +282,16 @@ class NPUW4A8MXFP4MoEMethod(_NPUMoEMethodBase):
     def __init__(self, dynamic_quant_kwargs=_DEFAULT_DYNAMIC_QUANT):
         super().__init__(quant_config=None)
         self.dynamic_quant_kwargs = dynamic_quant_kwargs
+        # Fused gmm1 (matmul + swiglu + requant in one aclnn kernel). The v2 op
+        # accepts FP4 weights via weight_scale/weight_dtype — verified on A5
+        # (llm/probe_mxfp4_gmm_swiglu_quant.py: same numerics as the unfused
+        # chain modulo the output fp8 requant, which the unfused chain also
+        # applies before gmm2).
+        self.use_fused_gmm1 = True
+        self.fused_matmul = GroupedMatmulSwigluQuant()
+        self.hidden_states_quantizer = HiddenStatesDynamicQuant(
+            quant_dtype=torch.float8_e4m3fn
+        )
 
     def process_weights_after_loading(
         self, layer: torch.nn.Module, weight_prefix: str
@@ -340,6 +350,57 @@ class NPUW4A8MXFP4MoEMethod(_NPUMoEMethodBase):
             dynamic_quant_kwargs=dynamic_quant_kwargs,
         )
 
+    def apply_fused_gmm1_swiglu(
+        self,
+        quant_info: "AscendQuantInfo",
+        hidden_states: torch.Tensor,
+        expert_tokens: torch.Tensor,
+        pertoken_scale: Optional[torch.Tensor],
+        group_list_type,
+    ) -> Tuple[torch.Tensor, torch.Tensor]:
+        """gmm1 + swiglu + requant in one kernel (fused MXFP4 path).
+
+        Mirrors NPUMXFP8MoEMethod.apply_fused_gmm1_swiglu but passes the FP4
+        weight dtype and the e8m0 weight_scale. Returns (e4m3 activations,
+        e8m0 block scale) ready for the w2 gmm.
+
+        The dispatcher hands over BF16 (see process_weights_after_loading), so
+        pertoken_scale is normally None and the activation quant happens here.
+        """
+        fp4_dtype = _get_float4_e2m1fn_x2_dtype()
+        if fp4_dtype is None:
+            raise RuntimeError("NPU W4A8 MXFP MoE requires float4 support.")
+        e8m0_dtype = _require_e8m0_dtype()
+
+        if pertoken_scale is None:
+            hidden_states, pertoken_scale = self.hidden_states_quantizer(hidden_states)
+        else:
+            # flat [T, K//32] -> pair form [T, K//64, 2]; identity if already
+            # pair-split.
+            pertoken_scale = pertoken_scale.reshape(
+                hidden_states.shape[0], hidden_states.shape[1] // 64, 2
+            )
+
+        return self.fused_matmul.forward(
+            quant_info,
+            "w13",
+            hidden_states,
+            expert_tokens.to(torch.int64),
+            group_list_type=group_list_type,
+            transposed=True,
+            weight_scale=[quant_info.w13_weight_scale],
+            x_scale=pertoken_scale,
+            dequant_mode=2,
+            quant_mode=2,
+            dequant_dtype=torch.float32,
+            quant_dtype=torch.float8_e4m3fn,
+            # e4m3 is implicit for x; FP4 must be passed for the weight.
+            x_dtype=None,
+            weight_dtype=fp4_dtype,
+            weight_scale_dtype=e8m0_dtype,
+            x_scale_dtype=e8m0_dtype,
+        )
+
 
 # ---------------------------------------------------------------------------
 #  NPUW4A4MXFP4MoEMethod
diff --git a/python/sglang/srt/layers/moe/moe_runner/ascend.py b/python/sglang/srt/layers/moe/moe_runner/ascend.py
index a14285f35..82ebb0ffc 100644
--- a/python/sglang/srt/layers/moe/moe_runner/ascend.py
+++ b/python/sglang/srt/layers/moe/moe_runner/ascend.py
@@ -26,6 +26,15 @@ from sglang.srt.hardware_backend.npu.quantization.moe_methods import (
     NPUW4A8MXFP4MoEMethod,
     NPUW8A8Int8MoEMethod,
 )
+
+
+def _uses_fused_gmm1(kernel) -> bool:
+    """Whether gmm1 runs matmul+swiglu+requant fused (no separate activation)."""
+    if isinstance(kernel, NPUMXFP8MoEMethod):
+        return True
+    return isinstance(kernel, NPUW4A8MXFP4MoEMethod) and kernel.use_fused_gmm1
+
+
 from sglang.srt.layers.moe.moe_runner.base import (
     MoeQuantInfo,
     MoeRunnerConfig,
@@ -93,13 +102,15 @@ class AscendRunnerCore(MoeRunnerCore):
 
         kernel = config.layer.w2_kernel
 
-        if isinstance(kernel, NPUMXFP8MoEMethod):
-            # MXFP8 fuses gate/up + swiglu + requant into gmm1, so there is no
-            # separate activation step — run() skips it. Left None on purpose so
-            # that reaching for it fails loudly instead of silently applying an
-            # unfused swiglu to already-requantised activations. This holds for
-            # both dispatchers: ascend_tp gets its activation quant fused into
-            # routing, DeepEP dispatches bf16 and gmm1 quantises it itself.
+        if _uses_fused_gmm1(kernel):
+            # Fused methods (MXFP8; MXFP4 W4A8 via use_fused_gmm1) fold
+            # gate/up + swiglu + requant into gmm1, so there is no separate
+            # activation step — run() skips it. Left None on purpose so that
+            # reaching for it fails loudly instead of silently applying an
+            # unfused swiglu to already-requantised activations. This holds
+            # for both dispatchers: ascend_tp gets its activation quant fused
+            # into routing, DeepEP dispatches bf16 and gmm1 quantises it
+            # itself.
             self.activation = None
         elif (
             isinstance(kernel, NPUW4A8MXFP4MoEMethod)
@@ -190,10 +201,10 @@ class AscendRunnerCore(MoeRunnerCore):
 
         w13_kernel = self.config.layer.w13_kernel
 
-        if isinstance(w13_kernel, NPUMXFP8MoEMethod):
+        if _uses_fused_gmm1(w13_kernel):
             # --- w13 projection + activation, fused into one kernel ---
-            # MXFP8 gmm1 returns activations already requantised for gmm2, so
-            # there is no separate activation step to run.
+            # The fused gmm1 returns activations already requantised for gmm2,
+            # so there is no separate activation step to run.
             hidden_states, pertoken_scale = w13_kernel.apply_fused_gmm1_swiglu(
                 quant_info,
                 x,