diff --git a/python/sglang/srt/layers/moe/moe_runner/deep_gemm.py b/python/sglang/srt/layers/moe/moe_runner/deep_gemm.py
index a814b5d23..4c3fda886 100644
--- a/python/sglang/srt/layers/moe/moe_runner/deep_gemm.py
+++ b/python/sglang/srt/layers/moe/moe_runner/deep_gemm.py
@@ -872,7 +872,7 @@ def _varlen_deep_gemm_silu_mul_quant(
     )
 
     use_jit_ep_activation = envs.SGLANG_OPT_USE_JIT_EP_ACTIVATION.get()
-    if N % 4 != 0 or G % 4 != 0:
+    if N % 4 != 0 or G % 4 != 0 or D // 8 < E:
         use_jit_ep_activation = False
 
     if use_jit_ep_activation: