diff --git a/python/sglang/srt/layers/quantization/modelopt_quant.py b/python/sglang/srt/layers/quantization/modelopt_quant.py
index c27efda65..af525600a 100755
--- a/python/sglang/srt/layers/quantization/modelopt_quant.py
+++ b/python/sglang/srt/layers/quantization/modelopt_quant.py
@@ -1799,10 +1799,15 @@ class ModelOptNvFp4FusedMoEMethod(FusedMoEMethodBase):
         )
         layer.register_parameter("w13_weight_scale", w13_weight_scale)
 
-        # Only use `swizzle_blockscale` for shapes, not for real content
-        layer.w13_blockscale_swizzled = Parameter(
-            swizzle_blockscale(layer.w13_weight_scale), requires_grad=False
-        )
+        # TRTLLM replaces blockscale_swizzled with an alias to weight_scale
+        # during process_weights_after_loading, so skip the expensive
+        # swizzle+allocate here to avoid GPU memory fragmentation
+        if self.enable_flashinfer_trtllm_moe:
+            layer.w13_blockscale_swizzled = None
+        else:
+            layer.w13_blockscale_swizzled = Parameter(
+                swizzle_blockscale(layer.w13_weight_scale), requires_grad=False
+            )
 
         w2_weight_scale = ModelWeightParameter(
             data=torch.empty(
@@ -1817,9 +1822,12 @@ class ModelOptNvFp4FusedMoEMethod(FusedMoEMethodBase):
         )
         layer.register_parameter("w2_weight_scale", w2_weight_scale)
 
-        layer.w2_blockscale_swizzled = Parameter(
-            swizzle_blockscale(layer.w2_weight_scale), requires_grad=False
-        )
+        if self.enable_flashinfer_trtllm_moe:
+            layer.w2_blockscale_swizzled = None
+        else:
+            layer.w2_blockscale_swizzled = Parameter(
+                swizzle_blockscale(layer.w2_weight_scale), requires_grad=False
+            )
 
         from sglang.srt.layers.moe.fused_moe_triton import FusedMoeWeightScaleSupported
 
diff --git a/python/sglang/srt/layers/quantization/utils.py b/python/sglang/srt/layers/quantization/utils.py
index 99e3218cf..6c5aed185 100644
--- a/python/sglang/srt/layers/quantization/utils.py
+++ b/python/sglang/srt/layers/quantization/utils.py
@@ -687,10 +687,31 @@ def prepare_static_weights_for_trtllm_fp4_moe(
         num_experts, hidden_size, intermediate_size // 16
     )  # fp8 scaling factors
 
-    gemm1_weights_fp4_shuffled = []
-    gemm1_scales_fp4_shuffled = []
-    gemm2_weights_fp4_shuffled = []
-    gemm2_scales_fp4_shuffled = []
+    # Pre-allocate output tensors so per-expert shuffles write directly into
+    # contiguous slices instead of building lists + torch.stack().  This avoids
+    # O(num_experts) transient GPU allocations whose freed blocks fragment the
+    # CUDA address space
+    gemm1_weights_fp4_shuffled = torch.empty_like(gemm1_weights_fp4.view(torch.uint8))
+    gemm2_weights_fp4_shuffled = torch.empty_like(gemm2_weights_fp4.view(torch.uint8))
+
+    # Pre-allocate scale output tensors and a reusable scratch buffer for
+    # the permuted input to nvfp4_block_scale_interleave.
+    # nvfp4_block_scale_interleave flattens its input to 1-D, so the
+    # per-expert output size equals the per-expert input numel.
+    def _alloc_scale_buffers(scales):
+        per_expert_shape = scales[0].view(torch.uint8).shape
+        per_expert_numel = scales[0].numel()
+        output = scales.new_empty((num_experts, per_expert_numel), dtype=torch.uint8)
+        scratch = torch.empty(per_expert_shape, dtype=torch.uint8, device=scales.device)
+        return output, scratch
+
+    gemm1_scales_fp4_shuffled, g1s_scratch = _alloc_scale_buffers(
+        gemm1_scales_linear_fp4
+    )
+    gemm2_scales_fp4_shuffled, g2s_scratch = _alloc_scale_buffers(
+        gemm2_scales_linear_fp4
+    )
+
     for i in range(num_experts):
         permute_indices = _maybe_get_cached_w3_w1_permute_indices(
             _cache_permute_indices,
@@ -698,11 +719,9 @@ def prepare_static_weights_for_trtllm_fp4_moe(
             epilogue_tile_m,
             is_gated_act_gemm=is_gated,
         )
-        gemm1_weights_fp4_shuffled.append(
-            gemm1_weights_fp4[i]
-            .view(torch.uint8)[permute_indices.to(gemm1_weights_fp4.device)]
-            .contiguous()
-        )
+        gemm1_weights_fp4_shuffled[i] = gemm1_weights_fp4[i].view(torch.uint8)[
+            permute_indices.to(gemm1_weights_fp4.device)
+        ]
 
         permute_sf_indices = _maybe_get_cached_w3_w1_permute_indices(
             _cache_permute_indices,
@@ -711,26 +730,23 @@ def prepare_static_weights_for_trtllm_fp4_moe(
             num_elts_per_sf=16,
             is_gated_act_gemm=is_gated,
         )
-        gemm1_scales_fp4_shuffled.append(
-            nvfp4_block_scale_interleave(
-                gemm1_scales_linear_fp4[i]
-                .view(torch.uint8)[
-                    permute_sf_indices.to(gemm1_scales_linear_fp4.device)
-                ]
-                .contiguous()
-            )
+        # Reuse scratch buffer for the permuted scale input
+        torch.index_select(
+            gemm1_scales_linear_fp4[i].view(torch.uint8),
+            0,
+            permute_sf_indices.to(gemm1_scales_linear_fp4.device),
+            out=g1s_scratch,
         )
+        gemm1_scales_fp4_shuffled[i] = nvfp4_block_scale_interleave(g1s_scratch)
 
         permute_indices = get_w2_permute_indices_with_cache(
             _cache_permute_indices,
             gemm2_weights_fp4[i].view(torch.uint8),
             epilogue_tile_m,
         )
-        gemm2_weights_fp4_shuffled.append(
-            gemm2_weights_fp4[i]
-            .view(torch.uint8)[permute_indices.to(gemm2_weights_fp4.device)]
-            .contiguous()
-        )
+        gemm2_weights_fp4_shuffled[i] = gemm2_weights_fp4[i].view(torch.uint8)[
+            permute_indices.to(gemm2_weights_fp4.device)
+        ]
 
         permute_sf_indices = get_w2_permute_indices_with_cache(
             _cache_permute_indices,
@@ -738,30 +754,24 @@ def prepare_static_weights_for_trtllm_fp4_moe(
             epilogue_tile_m,
             num_elts_per_sf=16,
         )
-        gemm2_scales_fp4_shuffled.append(
-            nvfp4_block_scale_interleave(
-                gemm2_scales_linear_fp4[i]
-                .view(torch.uint8)[
-                    permute_sf_indices.to(gemm2_scales_linear_fp4.device)
-                ]
-                .contiguous()
-            )
+        torch.index_select(
+            gemm2_scales_linear_fp4[i].view(torch.uint8),
+            0,
+            permute_sf_indices.to(gemm2_scales_linear_fp4.device),
+            out=g2s_scratch,
         )
+        gemm2_scales_fp4_shuffled[i] = nvfp4_block_scale_interleave(g2s_scratch)
 
-    # Stack weights for all experts
-    gemm1_weights_fp4_shuffled = torch.stack(gemm1_weights_fp4_shuffled)
-    gemm1_scales_fp4_shuffled = (
-        torch.stack(gemm1_scales_fp4_shuffled)
-        .view(torch.float8_e4m3fn)
-        .reshape(num_experts, gemm1_rows, hidden_size // 16)
-    )
+    del g1s_scratch, g2s_scratch
 
-    gemm2_weights_fp4_shuffled = torch.stack(gemm2_weights_fp4_shuffled)
-    gemm2_scales_fp4_shuffled = (
-        torch.stack(gemm2_scales_fp4_shuffled)
-        .view(torch.float8_e4m3fn)
-        .reshape(num_experts, hidden_size, intermediate_size // 16)
-    )
+    # Weight outputs stay as uint8 (FP4 packed) — the TRTLLM kernel expects this.
+    gemm1_scales_fp4_shuffled = gemm1_scales_fp4_shuffled.view(
+        torch.float8_e4m3fn
+    ).reshape(num_experts, gemm1_rows, hidden_size // 16)
+
+    gemm2_scales_fp4_shuffled = gemm2_scales_fp4_shuffled.view(
+        torch.float8_e4m3fn
+    ).reshape(num_experts, hidden_size, intermediate_size // 16)
     return (
         gemm1_weights_fp4_shuffled,
         gemm1_scales_fp4_shuffled,