diff --git a/python/sglang/srt/mem_cache/unified_radix_cache.py b/python/sglang/srt/mem_cache/unified_radix_cache.py
index 1bde47c5d..34e00ae19 100644
--- a/python/sglang/srt/mem_cache/unified_radix_cache.py
+++ b/python/sglang/srt/mem_cache/unified_radix_cache.py
@@ -6,7 +6,7 @@ import threading
 import time
 from array import array
 from collections import defaultdict
-from functools import lru_cache, partial
+from functools import partial
 from queue import Empty
 from typing import TYPE_CHECKING, Any, Optional
 
@@ -114,7 +114,6 @@ class UnifiedTreeNode:
             return None
         return self.hash_value[-1]
 
-    @lru_cache(maxsize=1)
     def get_prefix_hash_values(self, node: UnifiedTreeNode) -> list[str]:
         if node is None or node.hash_value is None:
             return []
diff --git a/test/registered/unit/mem_cache/test_unified_radix_cache_unittest.py b/test/registered/unit/mem_cache/test_unified_radix_cache_unittest.py
index dc0110242..4cb531965 100644
--- a/test/registered/unit/mem_cache/test_unified_radix_cache_unittest.py
+++ b/test/registered/unit/mem_cache/test_unified_radix_cache_unittest.py
@@ -169,6 +169,40 @@ class TestUnifiedRadixComponentRegistryOverride(CustomTestCase):
         self.assertIsNot(COMPONENT_REGISTRY[ComponentType.FULL], _FakeFullComponent)
 
 
+class TestUnifiedTreeNodeGetPrefixHashValues(CustomTestCase):
+    def test_get_prefix_hash_values_not_shared_across_calls(self):
+        """Regression guard for cached mutable prefix hash lists (#26177)."""
+
+        def make_node():
+            return UnifiedTreeNode(tree_components=(ComponentType.FULL,))
+
+        root = make_node()
+        n1 = make_node()
+        n1.parent = root
+        n1.hash_value = ["h1"]
+        n2 = make_node()
+        n2.parent = n1
+        n2.hash_value = ["h2"]
+        n3 = make_node()
+        n3.parent = n2
+        n3.hash_value = ["h3"]
+
+        first = n3.get_prefix_hash_values(n2)
+        self.assertEqual(first, ["h1", "h2"])
+
+        # Mimic downstream storage code that extends `prefix_keys` in place.
+        first += ["h3"]
+
+        second = n3.get_prefix_hash_values(n2)
+        self.assertEqual(second, ["h1", "h2"])
+        self.assertIsNot(second, first)
+
+        n4 = make_node()
+        n4.parent = n3
+        n4.hash_value = ["h4"]
+        self.assertEqual(n4.get_prefix_hash_values(n3), ["h1", "h2", "h3"])
+
+
 def build_fixture(cfg: CacheConfig, *, enable_kv_cache_events: bool = False):
     """Create (tree, allocator, req_to_token_pool) from a CacheConfig."""
     server_args = ServerArgs(model_path="dummy", page_size=cfg.page_size)