diff --git a/python/sglang/multimodal_gen/test/server/gpu_cases.py b/python/sglang/multimodal_gen/test/server/gpu_cases.py
index c02ad7472..a78aef40d 100644
--- a/python/sglang/multimodal_gen/test/server/gpu_cases.py
+++ b/python/sglang/multimodal_gen/test/server/gpu_cases.py
@@ -997,6 +997,20 @@ STANDALONE_FILES = {
     ],
 }
 
+# test_update_weights_from_disk fails deterministically on ROCm: the diffusion
+# weight-update-from-disk reload path does not reconcile the diffusers
+# checkpoint layout with the sglang transformer parameters (shape mismatch ->
+# HTTP 400). Tracked in #31924. NVIDIA does not run standalone files, so this
+# test is AMD-only; skip it on ROCm until the reload path is fixed. Remove
+# this block (keeping the STANDALONE_FILES / est-time entry above) to
+# re-enable once #31924 lands.
+if current_platform.is_hip():
+    STANDALONE_FILES["1-gpu"] = [
+        f
+        for f in STANDALONE_FILES["1-gpu"]
+        if f != "../single_test_file/test_update_weights_from_disk.py"
+    ]
+
 # New standalone files may omit an estimate once to learn the real CI runtime.
 # CI will use a fallback estimate for sharding, run the test, then print a
 # measured value that must be copied into STANDALONE_FILE_EST_TIMES.