diff --git a/.github/workflows/nightly-test-amd-rocm720.yml b/.github/workflows/nightly-test-amd-rocm720.yml
index a4845fb00..b01544daf 100644
--- a/.github/workflows/nightly-test-amd-rocm720.yml
+++ b/.github/workflows/nightly-test-amd-rocm720.yml
@@ -1064,7 +1064,8 @@ jobs:
 
   nightly-8-gpu-mi35x-deepseek-r1-mxfp4-tp4-rocm720:
     if: (github.repository == 'sgl-project/sglang' || github.event_name == 'pull_request') && (!(inputs.job_filter || inputs.job_select) || (inputs.job_filter || inputs.job_select) == 'all' || contains(format(',{0},', inputs.job_filter || inputs.job_select), ',nightly-8-gpu-mi35x-deepseek-r1-mxfp4-tp4-rocm720,'))
-    runs-on: linux-mi35x-gpu-8
+    # TP=4 workload: runs on the dedicated 4-GPU mi35x slice, not a whole 8-GPU node.
+    runs-on: linux-mi35x-gpu-4
     steps:
       - name: Checkout code
         uses: actions/checkout@v4
@@ -1760,7 +1761,8 @@ jobs:
 
   nightly-4-gpu-mi35x-minimax-m25-rocm720:
     if: (github.repository == 'sgl-project/sglang' || github.event_name == 'pull_request') && (!(inputs.job_filter || inputs.job_select) || (inputs.job_filter || inputs.job_select) == 'all' || contains(format(',{0},', inputs.job_filter || inputs.job_select), ',nightly-4-gpu-mi35x-minimax-m25-rocm720,'))
-    runs-on: linux-mi35x-gpu-8
+    # TP=4 workload: runs on the dedicated 4-GPU mi35x slice, not a whole 8-GPU node.
+    runs-on: linux-mi35x-gpu-4
     steps:
       - name: Checkout code
         uses: actions/checkout@v4
diff --git a/.github/workflows/nightly-test-amd.yml b/.github/workflows/nightly-test-amd.yml
index f34c27257..1d09a53b3 100644
--- a/.github/workflows/nightly-test-amd.yml
+++ b/.github/workflows/nightly-test-amd.yml
@@ -1068,7 +1068,8 @@ jobs:
 
   nightly-8-gpu-mi35x-deepseek-r1-mxfp4-tp4:
     if: (github.repository == 'sgl-project/sglang' || github.event_name == 'pull_request') && (!(inputs.job_filter || inputs.job_select) || (inputs.job_filter || inputs.job_select) == 'all' || contains(format(',{0},', inputs.job_filter || inputs.job_select), ',nightly-8-gpu-mi35x-deepseek-r1-mxfp4-tp4,'))
-    runs-on: linux-mi35x-gpu-8
+    # TP=4 workload: runs on the dedicated 4-GPU mi35x slice, not a whole 8-GPU node.
+    runs-on: linux-mi35x-gpu-4
     steps:
       - name: Checkout code
         uses: actions/checkout@v4
@@ -1616,7 +1617,8 @@ jobs:
 
   nightly-4-gpu-mi35x-minimax-m25:
     if: (github.repository == 'sgl-project/sglang' || github.event_name == 'pull_request') && (!(inputs.job_filter || inputs.job_select) || (inputs.job_filter || inputs.job_select) == 'all' || contains(format(',{0},', inputs.job_filter || inputs.job_select), ',nightly-4-gpu-mi35x-minimax-m25,'))
-    runs-on: linux-mi35x-gpu-8
+    # TP=4 workload: runs on the dedicated 4-GPU mi35x slice, not a whole 8-GPU node.
+    runs-on: linux-mi35x-gpu-4
     steps:
       - name: Checkout code
         uses: actions/checkout@v4
diff --git a/.github/workflows/pr-test-amd-rocm720.yml b/.github/workflows/pr-test-amd-rocm720.yml
index dd1c7f12e..0a193bbe8 100644
--- a/.github/workflows/pr-test-amd-rocm720.yml
+++ b/.github/workflows/pr-test-amd-rocm720.yml
@@ -48,6 +48,7 @@ on:
           - stage-c-test-large-8-gpu-amd-mi35x-rocm720
           - stage-b-test-large-8-gpu-mi35x-disaggregation-amd-rocm720
           - stage-c-test-4-gpu-amd-rocm720
+          - stage-c-test-4-gpu-amd-mi35x-rocm720
           - dsv4-flash-fp4-fp8-amd-rocm720
           - dsv4-pro-fp4-amd-rocm720
       target_stage:
@@ -988,7 +989,48 @@ jobs:
       fail-fast: false
       matrix:
         runner: [linux-mi35x-gpu-8]
-        part: [0, 1]
+        part: [0]
+    runs-on: ${{matrix.runner}}
+    steps:
+      - name: Checkout code
+        uses: actions/checkout@v4
+        with:
+          ref: ${{ inputs.pr_head_sha || inputs.ref || github.sha }}
+
+      - name: Ensure VRAM is clear
+        run: bash scripts/ci/amd/ensure_vram_clear.sh rocm
+
+      - name: Start CI container
+        run: bash scripts/ci/amd/amd_ci_start_container.sh --rocm-version rocm720
+        env:
+          GITHUB_WORKSPACE: ${{ github.workspace }}
+
+      - name: Install dependencies
+        run: bash scripts/ci/amd/amd_ci_install_dependency.sh
+      - name: Run test
+        timeout-minutes: 120
+        run: |
+          bash scripts/ci/amd/amd_ci_exec.sh -w "/sglang-checkout/test" python3 run_suite.py --hw amd --suite stage-c-test-large-8-gpu-amd-mi35x --auto-partition-id ${{ matrix.part }} --auto-partition-size 1 --timeout-per-file 3600 ${{ needs.check-changes.outputs.continue_on_error == 'true' && '--continue-on-error' || '' }}
+
+  # MI35x stage-c tests that only need 4 GPUs (e.g. DeepSeek-R1-MXFP4 TP=4),
+  # split off the 8-GPU mi35x suite onto the dedicated 4-GPU mi35x slice.
+  stage-c-test-4-gpu-amd-mi35x-rocm720:
+    needs: [check-changes]
+    if: |
+      always() &&
+      (
+        (contains(format(',{0},', inputs.target_stage || inputs.target_stage_select), ',stage-c-test-4-gpu-amd-mi35x-rocm720,')) ||
+        (
+          !(inputs.target_stage || inputs.target_stage_select) &&
+          (!failure() && !cancelled()) &&
+          ((needs.check-changes.outputs.main_package == 'true') || (needs.check-changes.outputs.sgl_kernel == 'true'))
+        )
+      )
+    strategy:
+      fail-fast: false
+      matrix:
+        runner: [linux-mi35x-gpu-4]
+        part: [0]
     runs-on: ${{matrix.runner}}
     steps:
       - name: Checkout code
@@ -1009,7 +1051,7 @@ jobs:
       - name: Run test
         timeout-minutes: 60
         run: |
-          bash scripts/ci/amd/amd_ci_exec.sh -w "/sglang-checkout/test" python3 run_suite.py --hw amd --suite stage-c-test-large-8-gpu-amd-mi35x --auto-partition-id ${{ matrix.part }} --auto-partition-size 2 --timeout-per-file 3600 ${{ needs.check-changes.outputs.continue_on_error == 'true' && '--continue-on-error' || '' }}
+          bash scripts/ci/amd/amd_ci_exec.sh -w "/sglang-checkout/test" python3 run_suite.py --hw amd --suite stage-c-test-4-gpu-amd-mi35x --auto-partition-id ${{ matrix.part }} --auto-partition-size 1 --timeout-per-file 3600 ${{ needs.check-changes.outputs.continue_on_error == 'true' && '--continue-on-error' || '' }}
 
   # =============================================== Disaggregation ====================================================
   stage-b-test-large-8-gpu-mi35x-disaggregation-amd-rocm720:
@@ -1255,6 +1297,7 @@ jobs:
         stage-b-test-2-gpu-large-amd-rocm720,
         stage-b-test-large-8-gpu-mi35x-disaggregation-amd-rocm720,
         stage-c-test-4-gpu-amd-rocm720,
+        stage-c-test-4-gpu-amd-mi35x-rocm720,
         stage-c-test-large-8-gpu-amd-rocm720,
         stage-c-test-large-8-gpu-amd-mi35x-rocm720,
 
diff --git a/.github/workflows/pr-test-amd.yml b/.github/workflows/pr-test-amd.yml
index a08d00967..427731703 100644
--- a/.github/workflows/pr-test-amd.yml
+++ b/.github/workflows/pr-test-amd.yml
@@ -35,6 +35,7 @@ on:
           - multimodal-gen-test-1-gpu-amd
           - multimodal-gen-test-2-gpu-amd
           - stage-c-test-4-gpu-amd
+          - stage-c-test-4-gpu-amd-mi35x
           - stage-c-test-large-8-gpu-amd
           - stage-c-test-large-8-gpu-amd-mi35x
           - stage-b-test-large-8-gpu-mi35x-disaggregation-amd
@@ -1036,7 +1037,50 @@ jobs:
       fail-fast: false
       matrix:
         runner: [linux-mi35x-gpu-8]
-        part: [0, 1]
+        part: [0]
+    runs-on: ${{matrix.runner}}
+    steps:
+      - name: Checkout code
+        uses: actions/checkout@v4
+        with:
+          ref: ${{ inputs.pr_head_sha || inputs.ref || github.sha }}
+
+      - name: Ensure VRAM is clear
+        run: bash scripts/ci/amd/ensure_vram_clear.sh rocm
+
+      - name: Start CI container
+        run: bash scripts/ci/amd/amd_ci_start_container.sh
+        env:
+          GITHUB_WORKSPACE: ${{ github.workspace }}
+
+      - name: Install dependencies
+        run: bash scripts/ci/amd/amd_ci_install_dependency.sh
+
+      - name: Run test
+        timeout-minutes: 120
+        run: |
+          bash scripts/ci/amd/amd_ci_exec.sh -w "/sglang-checkout/test" python3 run_suite.py --hw amd --suite stage-c-test-large-8-gpu-amd-mi35x --auto-partition-id ${{ matrix.part }} --auto-partition-size 1 --timeout-per-file 3600 ${{ needs.check-changes.outputs.continue_on_error == 'true' && '--continue-on-error' || '' }}
+
+  # MI35x stage-c tests that only need 4 GPUs (e.g. DeepSeek-R1-MXFP4 TP=4).
+  # Split off the 8-GPU mi35x suite so they no longer hold a whole 8-GPU node
+  # and instead run on the dedicated 4-GPU mi35x slice.
+  stage-c-test-4-gpu-amd-mi35x:
+    needs: [check-changes, call-gate, wait-for-stage-b-amd]
+    if: |
+      always() &&
+      (
+        (contains(format(',{0},', inputs.target_stage || inputs.target_stage_select), ',stage-c-test-4-gpu-amd-mi35x,')) ||
+        (
+          !(inputs.target_stage || inputs.target_stage_select) &&
+          ((github.event_name == 'schedule') || (!failure() && !cancelled())) &&
+          ((needs.check-changes.outputs.main_package == 'true') || (needs.check-changes.outputs.sgl_kernel == 'true'))
+        )
+      )
+    strategy:
+      fail-fast: false
+      matrix:
+        runner: [linux-mi35x-gpu-4]
+        part: [0]
     runs-on: ${{matrix.runner}}
     steps:
       - name: Checkout code
@@ -1058,7 +1102,7 @@ jobs:
       - name: Run test
         timeout-minutes: 60
         run: |
-          bash scripts/ci/amd/amd_ci_exec.sh -w "/sglang-checkout/test" python3 run_suite.py --hw amd --suite stage-c-test-large-8-gpu-amd-mi35x --auto-partition-id ${{ matrix.part }} --auto-partition-size 2 --timeout-per-file 3600 ${{ needs.check-changes.outputs.continue_on_error == 'true' && '--continue-on-error' || '' }}
+          bash scripts/ci/amd/amd_ci_exec.sh -w "/sglang-checkout/test" python3 run_suite.py --hw amd --suite stage-c-test-4-gpu-amd-mi35x --auto-partition-id ${{ matrix.part }} --auto-partition-size 1 --timeout-per-file 3600 ${{ needs.check-changes.outputs.continue_on_error == 'true' && '--continue-on-error' || '' }}
 
   # =============================================== Disaggregation ====================================================
   stage-b-test-large-8-gpu-mi35x-disaggregation-amd:
@@ -1194,6 +1238,7 @@ jobs:
         stage-b-test-2-gpu-large-amd,
         stage-b-test-large-8-gpu-mi35x-disaggregation-amd,
         stage-c-test-4-gpu-amd,
+        stage-c-test-4-gpu-amd-mi35x,
         stage-c-test-large-8-gpu-amd,
         stage-c-test-large-8-gpu-amd-mi35x,
       ]
diff --git a/test/registered/amd/test_deepseek_r1_mxfp4_8gpu.py b/test/registered/amd/test_deepseek_r1_mxfp4_4gpu.py
similarity index 91%
rename from test/registered/amd/test_deepseek_r1_mxfp4_8gpu.py
rename to test/registered/amd/test_deepseek_r1_mxfp4_4gpu.py
index e426ec694..23857582d 100644
--- a/test/registered/amd/test_deepseek_r1_mxfp4_8gpu.py
+++ b/test/registered/amd/test_deepseek_r1_mxfp4_4gpu.py
@@ -16,7 +16,7 @@ from sglang.test.test_utils import (
     write_github_step_summary,
 )
 
-register_amd_ci(est_time=3600, suite="stage-c-test-large-8-gpu-amd-mi35x")
+register_amd_ci(est_time=3600, suite="stage-c-test-4-gpu-amd-mi35x")
 
 DEEPSEEK_R1_MODEL_PATH = "amd/DeepSeek-R1-MXFP4-Preview"
 SERVER_LAUNCH_TIMEOUT = 1800
@@ -30,12 +30,12 @@ class TestDeepseekR1MXFP4(CustomTestCase):
 
         # Workaround: AITER custom all-gather corrupts CUDA-graph IPC buffer
         # registration and triggers a decode-time "Memory access fault" on
-        # MI35x TP=8. Disable until the AITER-side fix lands (see PR body).
+        # MI35x. Disable until the AITER-side fix lands (see PR body).
         envs.SGLANG_USE_AITER_AG.set(False)
 
         other_args = [
             "--tp",
-            "8",
+            "4",
             "--chunked-prefill-size",
             "131072",
             "--model-loader-extra-config",
@@ -90,7 +90,8 @@ class TestDeepseekR1MXFP4(CustomTestCase):
             write_github_step_summary(
                 f"### test_bs_1_speed (deepseek-r1-mxfp4)\n" f"{speed=:.2f} token/s\n"
             )
-        self.assertGreater(speed, 75)
+        # Report-only: the previous >75 tok/s gate was calibrated for TP=8.
+        # Decode throughput at TP=4 differs; re-calibrate before re-enabling.
 
 
 class TestDeepseekR1MXFP4MTP(CustomTestCase):
@@ -105,7 +106,7 @@ class TestDeepseekR1MXFP4MTP(CustomTestCase):
 
         other_args = [
             "--tp",
-            "8",
+            "4",
             "--chunked-prefill-size",
             "131072",
             "--speculative-algorithm",
@@ -175,7 +176,8 @@ class TestDeepseekR1MXFP4MTP(CustomTestCase):
                 f"{speed=:.2f} token/s\n"
             )
             self.assertGreater(acc_length, 2.04)
-            self.assertGreater(speed, 150)
+            # Report-only: the previous >150 tok/s gate was calibrated for TP=8.
+            # Decode throughput at TP=4 differs; re-calibrate before re-enabling.
 
 
 if __name__ == "__main__":
diff --git a/test/run_suite.py b/test/run_suite.py
index de7d3247f..7d955630f 100644
--- a/test/run_suite.py
+++ b/test/run_suite.py
@@ -41,6 +41,7 @@ PER_COMMIT_SUITES = {
         "jit-kernel-unit-test-amd",
         "sgl-kernel-unit-test-2-gpu-amd",
         "stage-c-test-4-gpu-amd",
+        "stage-c-test-4-gpu-amd-mi35x",
         "stage-c-test-large-8-gpu-amd",
         "stage-c-test-large-8-gpu-amd-mi35x",
         # extra-a: label-gated PR opt-in suites in pr-test-amd-extra.yml